Discussion
The aim of this combined scoping and systematic review was to explore the scope of research into promotive/preventive AMH interventions across SSA and to gain insight into effectiveness and cultural tailoring of these interventions. A total of 79 papers were identified, related to 61 primary interventions. Although research into the topic is emerging with most papers published after 2015, the identified evidence was relatively limited in terms of target populations and geographical spread, with three countries (South Africa, Kenya or Uganda) accounting for 60% of the research. However, in terms of intervention aims, approaches and outcomes, the scope of research was broad. This was expected and reflects many possible pathways to promoting mental health and preventing mental illness either through psychosocial or structural interventions.
In addition to three mental health literacy interventions, this review found 30 psychosocial interventions, often targeting individual-level outcomes. Interventions had core components linked to creative-expressive approaches, cognitive–behavioural/socioemotional skills building and bereavement. Five of these were universal, school-based interventions, while most were targeted interventions, focused on orphans or HIV positive adolescents. Psychosocial skills-based components of these interventions appear similar to those reported in previous reviews.10 13 20 Included interventions had the primary aim of promoting mental health as the end goal, or as a clearly specified stop along the road to reducing risky behaviours and/or promoting physical health. Others were mainly intended to achieve another aim, but also measured mental health outcomes. This was particularly the case for the remaining 28 structural interventions, which included HIV prevention/management interventions; parenting/family strengthening interventions; economic livelihood interventions and gender equality interventions.
As also reported in previous reviews,17 19 20 heterogeneity in terms of programme content, delivery, duration and study sample made it difficult to draw general conclusions about the effectiveness of interventions as a whole. RCTs of three universal, school-based interventions (ERASE, RAP-A and a psychoeducational life skills programme44 50 108) showed promising results. The effectiveness of these skills-based interventions has been established in HICs108 109 and these studies now provide initial evidence of effective cross-cultural transferability of such approaches to SSA contexts. Indications of superior effectiveness for certain psychosocial interventions in certain target populations were not found. However, in the context of bereavement, memory therapy and a peer-support group for orphans38 52 were found to be effective. While a review of promotion interventions in LMICs20 concluded that multicomponent community-based interventions showed a positive impact, the current review adds further nuance to this conclusion. Namely, the strongest evidence of effectiveness came from economic livelihood interventions. Many RCTs of other structural, community-based interventions, such as HIV and mental health prevention interventions, showed mixed results. This does not necessarily mean that these interventions were not successful, as many measured symptom levels -often below clinical levels at the start of the intervention—as opposed to well-being indicators. Furthermore, the relatively short follow-up times of these interventions might not have been long enough to determine effect on diagnosable disorders. More high-quality, longitudinal studies that use appropriate analytical approaches are needed to establish the impact of prevention interventions on the onset of mental health disorders.
To gain the full picture on AMH prevention interventions in SSA, the current review should be read alongside a recent review on substance use prevention interventions, which found evidence of effectiveness for individual-focused interventions, rather than school-based approaches.110 This review also reported a limited geographical spread of studies across the region and includes an interesting discussion around the dominance of South-African research that we feel is also relevant for the current review.
Examples of cultural tailoring were found in 23 interventions, yet this was often at the surface level. At deep structure level, few interventions specified if and how they incorporated African worldviews and contexts (eg, related to spiritual beliefs). One of the interventions with the most contextualisation (ERASE) has led to good results, but further research is needed to understand how this impacts intervention effectiveness and/or accuracy of measurements. It should be noted, however, that few authors published details of the full intervention adaptation process from development to evaluation. This may mean that considerations of local context have been missed. The lack of clear reporting on adaptations made, could also be a reflection of the lack of a standardised, evidence-based framework for cultural adaptation.111
This review highlighted that most interventions were delivered in the context of HIV, either by targeting (AIDS) orphans, HIV positive adolescents, embedding HIV prevention approaches, or by framing poor mental health as a risk factor for risky sexual behaviour. While this shows a general responsiveness of interventions to the SSA context, it is important to recognise that many adolescents in SSA face significant daily adversities,8 regardless of their HIV or orphanhood status. All adolescents would reap the benefits of being mentally well. Universal, school-based approaches that foster multisectoral action would allow for a wide reach of generic mental health promotion and prevention activities. These are strongly recommended by the WHO since they are considered relatively easy to implement and less likely to cause stigmatisation compared with interventions that require screening.4 Yet, this review showed that there have so far been limited attempts to develop or adapt these in SSA. Teachers are often considered to be best placed to deliver school-based interventions, but their ability to do so may be inhibited by stigma and limited MH literacy.112 These approaches would, therefore, need to include adolescent-targeted as well as teacher-targeted components. For the latter, a potential resource might be the WHO manual for mental health in schools, aimed at building MH literacy in educators in resource-limited settings.113 Still, teacher-dependent interventions need to consider the potential burden on teachers who are often responsible for a large number of children and may have few opportunities for professional development in the face of challenges of teaching in a low-resource context.114 This could signal the need for non-teaching professionals to deliver school-based MH programmes.115
A major limitation of using school-based approaches for AMH promotion/prevention is that this would not reach adolescents outside of the school system. This specific population often includes a higher proportion of adolescents with increased vulnerability to MH conditions, such as orphans, those in informal settlements and street youth.114 While this review identified targeted interventions at individual or interpersonal/family level that could perhaps be scaled up to include a broader range of adolescents, it did not identify any universal interventions at community level (such as the Communities That Care approach116) aimed at forming community coalitions to prevent negative MH outcomes. Such interventions should also include specific stigma-reduction components, to combat the far-reaching negative impact of mental health-related stigma—present in many SSA communities—on health seeking behaviour and social inclusion.117
In terms of further research gaps, there were no studies that explored opportunities for national or regional scale-up and sustainability of promising interventions. Most economic livelihood studies built on the work of the same principal investigator in Uganda. Explorations of this work in other SSA settings should explore transferability of findings. There were also no studies that included elements related to suicide prevention, lifestyle approaches around exercise/nutrition and social media. Such components would make interventions responsive to contemporary developments in the region, including high rates of suicidal ideation and increasing obesity among adolescents.118 119
While we believe the rigorous and transparent design and the lack of language restrictions were significant strengths of this review, it also had some limitations. First, only interventions that were delivered to adolescents and that measured AMH outcomes were included. Because of this, some interventions that could be classed as AMH promotion interventions (eg, housing interventions, teacher-training) were not considered. Still, this review applied broad inclusion criteria, which led to the inclusion of a large number of heterogeneous interventions. As a result, it was felt that a meta-analysis was not possible, and the decision was made to focus on intervention types, rather than on psychosocial skills-based components to organise findings. Such a component-based approach might have allowed us to gain deeper insight into whether certain psychosocial exercises (eg, CBT vs mindfulness-based activities) showed superior effectiveness over others, as was explored by Skeen et al.10 Finally, this review did not include grey literature, which means we may have missed interventions delivered by implementers that do not have the capacity to publish.